Running head: Implicit sequence learning ABSTRACT Can we learn without awareness? Although this issue has been extensively explored through studies of implicit learning, there is currently no agreement about the extent to which knowledge can be acquired and projected onto performance in an unconscious way. The controversy, like that surrounding implicit memory, seems to be at least in part attributable to unquestioned acceptance of the unrealistic assumption that tasks are process-pure, that is, that a given task exclusively involves either implicit (...) or explicit knowledge. (shrink)

In cognitive neuroscience, dissociating the brain networks that ing—has thus become one of the best empirical situations subtend conscious and nonconscious memories constitutes a through which to study the mechanisms of implicit learning, very complex issue, both conceptually and methodologically.

69 Thompson-Schill, S.L. _et al. _(1997) Role of left inferior prefrontal cortex 59 Buckner, R.L. _et al. _(1996) Functional anatomic studies of memory in retrieval of semantic knowledge: a re-evaluation _Proc. Natl. Acad._ retrieval for auditory words and pictures _J. Neurosci. _16, 6219–6235 _Sci. U. S. A. _94, 14792–14797 60 Buckner, R.L. _et al. _(1995) Functional anatomical studies of explicit and 70 Baddeley, A. (1992) Working memory: the interface between memory implicit memory retrieval tasks _J. Neurosci. _15, 12–29 and cognition (...) _J. Cogn. Neurosci. _4, 281–288 61 Bäckman, L. _et al. _(1997) Brain activation in young and older adults 71 Petrides, M. (1994) Frontal lobes and behavior _Curr. Opin. Neurobiol._ during implicit and explicit retrieval _J. Cogn. Neurosci. _9, 378–391. (shrink)

How do we find out whether someone is conscious of some information or not? A simple answer is “We just ask them”! However, things are not so simple. Here, we review recent developments in the use of subjective and objective methods in implicit learning research and discuss the highly complex methodological problems that their use raises in the domain.

Perruchet and Vinter stop short of fully embracing the implications of their own SOC framework, and hence end up defending an implausible perspective on consciousness. We suggest instead that consciousness should be viewed as a graded dimension defined over quality of representation. This graded perspective eliminates the most problematic aspects of the cognitive unconscious without denying its existence altogether.

Using positron emission tomography (PET) and regional cerebral blood flow (rCBF) measurements, we investigated the cerebral correlates of consciousness in a sequence learning task through a novel application of the Process Dissociation Procedure, a behavioral paradigm that makes it possible to separately assess conscious and unconscious contributions to performance. Results show that the metabolic response in the anterior cingulate / mesial prefrontal cortex (ACC / MPFC) is exclusively and specifically correlated with the explicit component of performance during recollection of a (...) learned sequence. This suggests a significant role for the ACC / MPFC in the explicit processing of sequential material.  2003 Elsevier Science B.V. All rights reserved. (shrink)

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Walker proposes that procedural memory formation involves two specific stages of consolidation: wake-dependent stabilization, followed by sleep-dependent enhancement. If sleep-based enhancement of procedural memory formation is now well supported by evidence obtained at different levels of cognitive and neurophysiological organization, wake-dependent mechanisms for stabilization have not been demonstrated as convincingly, and still require more systematic characterization.

Several authors have argued that causes differ in the degree to which they are ‘specific’ to their effects. Woodward has used this idea to enrich his influential interventionist theory of causal explanation. Here we propose a way to measure causal specificity using tools from information theory. We show that the specificity of a causal variable is not well-defined without a probability distribution over the states of that variable. We demonstrate the tractability and interest of our proposed measure by measuring the (...) specificity of coding DNA and other factors in a simple model of the production of mRNA. (shrink)

It has been claimed that the ability to remember the past and the ability to project oneself into the future are intimately related. We sought support for this proposition by examining whether individual differences in dimensions that have been shown to affect memory for past events similarly influence the experience of projecting oneself into the future. We found that individuals with a higher capacity for visual imagery experienced more visual and other sensory details both when remembering past events and when (...) imagining future events. In addition, individuals who habitually use suppression to regulate their emotions experienced fewer sensory, contextual, and emotional details when representing both past and future events, while the use of reappraisal had no effect on either kind of events. These findings are consistent with the view that mental time travel into the past and into the future relies on similar mechanisms. (shrink)

According to some authors, emotions can be unconscious when they are unfelt or unnoticed. According to others, emotions are always conscious because they always have a phenomenology. The aim of this paper is to resolve the ongoing debate about the possibility for emotions to be unfelt. To do so, I focus on the notion of “unconscious emotions”. While this notion appears paradoxical, by way of a distinction between two meanings of emotional consciousness I show that it is not so. These (...) meanings are both compatible with the leading views of consciousness and they do not require one to distinguish different senses of “emotions” or “consciousness”. This distinction is helpful to define how emotions can be unconscious. (shrink)

The Corporate Social Performance (CSP) model (Wood, Acad Manag Rev 164:691–718, 1991) assesses a firm’s social responsibility at three levels of analysis—institutional, organizational and individual—and measures the resulting social outcomes. In this paper, we focus on the individual level of CSP, manifested in the managerial discretion of a firm’s principles, processes, and policies regarding social responsibilities. Specifically, we address the human resources management of employees as a way of promoting CSR values and producing socially minded outcomes. We show that applying (...) the humanist philosophy to the managerial discretion of a business organization leads to the creation of an “autonomy supportive work environment”—as defined by the self-determination theory—which in turn, facilitates the internalization of social values, citizenship behaviors, and cooperation. The objective of promoting self-determination at work (i.e., the core of a humanist management) fits well with the ontology of social responsibility since autonomy and consideration of individuals as moral actors are central tenets. Furthermore, we show that applying humanistic management philosophy to the discretion of managers can lead to socially responsible outcomes. First, intra-organizational stakeholders (e.g., employees) are treated with respect and focus is put on their well-being, satisfaction, and self-actualization at work. Second, as employees’ need of self-determination is addressed by managers, it is likely that pro-social behaviors toward other stakeholders of the organization will be adopted, leading to socially responsible outcomes for extra-organizational stakeholders (Gagné, Motiv Emot 77:58–75, 2003). Thus, this paper ultimately posits that humanistic management applied to the HRM can be a solution for developing and maintaining socially responsible outcomes as determined at the individual level of the CSP model, through managerial discretion. (shrink)

L'usage du terme «événement» recouvre plusieurs réalités. L'objectif de cet article est de confronter l'usage que les médias en font, avec ce que les chercheurs en sciences sociales en retiennent. Pour les journalistes, l'événement c'est un fait remarquable méritant un traitement spécial qui le mette en valeur. Pour les sciences sociales, il s'agit d'un phénomène qui est vécu comme rupture, par une société ou un collectif, et qui enclenche donc une recherche d'intelligibilité. Les deux logiques sont-elles amenées à se rencontrer? (...) Tout événement est-il reconnu et traité comme événement médiatique ou pas? Et inversement? Pour répondre à ces questions, cet article cerne les conditions d'émergence médiatique d'un événement à l'échelle internationale, ce que nous appelons la lecture événementielle des faits. Quatre conditions sont retenues: les critères d'intensité émotionnelle; l'accès au terrain et l'existence d'acteurs sociaux à même de fournir une interprétation événementielle; la possibilité de réencodage culturel des faits; le degré de concurrence avec d'autres faits éligibles au rang d'événement. Des schémas tentent de fournir une synthèse des cas de figure rencontrés.The use of the term "event" covers several realities. The objective of this paper is to compare the use that the media are, with what social scientists hold. For journalists, the event is a remarkable fact deserving special treatment that emphasizes it. In the social sciences, it is a phenomenon that is experienced as a rupture, a company or a group, and then clicks a search for intelligibility. The two logics are brought to meet them? Any event it is recognized and treated as a media event or not? And vice versa? To answer these questions, this article identifies the conditions for the emergence of a media event at the international level, what we call the event reading of the facts. Four conditions were used: the criteria of emotional intensity, access to land and the existence of social actors able to provide an interpretation event, the possibility of re-encoding cultural facts, the degree of competition with other facts eligible for ranking event. Schemes attempt to provide an overview of the situations encountered. (shrink)

Wilson et al. focus on one class of AGL tasks: the cognitively demanding task of detecting non‐adjacent dependencies (NADs) among items. They provide a typology of the different types of NADs in natural languages and in AGL tasks. A range of cues affect NAD learning, ranging from the variability and number of intervening elements to the presence of shared prosodic cues between the dependent items. These cues, important for humans to discover non‐adjacent dependencies, are also found to facilitate NAD learning (...) in several nonhuman animal species. (shrink)

Recent work by Brian Skyrms offers a very general way to think about how information flows and evolves in biological networks—from the way monkeys in a troop communicate to the way cells in a body coordinate their actions. A central feature of his account is a way to formally measure the quantity of information contained in the signals in these networks. In this article, we argue there is a tension between how Skyrms talks of signalling networks and his formal measure (...) of information. Although Skyrms refers to both how information flows through networks and that signals carry information, we show that his formal measure only captures the latter. We then suggest that to capture the notion of flow in signalling networks, we need to treat them as causal networks. This provides the formal tools to define a measure that does capture flow, and we do so by drawing on recent work defining causal specificity. Finally, we suggest that this new measure is crucial if we wish to explain how evolution creates information. For signals to play a role in explaining their own origins and stability, they can’t just carry information about acts; they must be difference-makers for acts. _1_ Signalling, Evolution, and Information _2_ Skyrms’s Measure of Information _3_ Carrying Information versus Information Flow _3.1_ Example 1 _3.2_ Example 2 _3.3_ Example 3 _4_ Signalling Networks Are Causal Networks _4.1_ Causal specificity _4.2_ Formalizing causal specificity _5_ Information Flow as Causal Control _5.1_ Example 1 _5.2_ Examples 2 and 3 _5.3_ Average control implicitly ‘holds fixed’ other pathways _6_ How Does Evolution Create Information? _7_ Conclusion Appendix >. (shrink)

Wilson et al. focus on one class of AGL tasks: the cognitively demanding task of detecting non‐adjacent dependencies (NADs) among items. They provide a typology of the different types of NADs in natural languages and in AGL tasks. A range of cues affect NAD learning, ranging from the variability and number of intervening elements to the presence of shared prosodic cues between the dependent items. These cues, important for humans to discover non‐adjacent dependencies, are also found to facilitate NAD learning (...) in several nonhuman animal species. (shrink)

This paper suggests that autistic people relate to themselves via a third-person perspective, an objective and explicit mode of access, while neurotypical people tend to access the different dimensions of their self through a first-person perspective. This approach sheds light on autistic traits involving interactions with others, usage of narratives, sensitivity and interoception, and emotional consciousness. Autistic people seem to access these dimensions through comparatively indirect and effortful processes, while neurotypical development enables a more intuitive sense of self.

Strategies based on performance measurement and feedback are commonly used to support quality improvement among nurses. These strategies require practice change, which, for nurses, rely to a large extent on their capacity to coordinate with each other effectively. However, the levers for coordinated action are difficult to mobilize. This discussion paper offers a theoretical reflection on the challenges related to coordinating nurses' actions in the context of practice changes initiated by performance measurement and feedback strategies. We explore how Jürgen Habermas' (...) theory of Communicative Action may shed light on the issues underlying nurses' collective actions and self‐determination in practice change and the implications for the design of strategies based on performance measurement and feedback. Based on this theory, we propose differences between communicative and functional coordination according to the nature of the actions and the purposes involved. The domains of action underlying these coordination processes, which Habermas referred to as the lifeworld and the system, are then used to draw a parallel with aspects of nursing practice. Further exploration of these concepts allows us to consider the tensions between the demands of the system and the self‐determination of nurses within their practice. (shrink)

How should we seek to account for the qualitative aspect of emotion? Strong intentionalism presents one promising avenue for such an account. According to strong intentionalism, the phenomenology of a mental state is entirely determined by that state's intentional content. Given that many views of the emotions have it that the intentionality and phenomenology of the emotions are very closely related, this makes strong intentionalism an especially promising route. However, strong intentionalism has rarely been defended for emotions and, we argue, (...) where it has, it has failed to be explanatory. This paper proposes a new explanatory form of strong intentionalism about emotion. We call it personal intentionalism. According to this view, the qualitative features of emotion are fully determined by the emotion's intentional content. This content varies inter- and intraindividually, according to one's cares and concerns, as well as one's other mental states. We assess its compatibility with theories of consciousness. (shrink)

Adopting a functionalist perspective, we emphasize the interest of considering imitation as a single capacity with two functions: communication and learning. These two functions both imply such capacities as detection of novelty, attraction toward moving stimuli and perception-action coupling. We propose that the main difference between the processes involved in the two functions is that, in the case of learning, the dynamics is internal to the system constituted by an individual whereas in the case of communication, the dynamics concerns the (...) system composed by the perception of one individual coupled with the action of the other.In this paper, we compare the first developmental steps of imitation in three populations: typically developing children, children with autism, and robots. We show evidence of strong correlations between imitating and being imitated in typical infants and low-functioning children with autism. Relying on this evidence, the robotic perspective is to provide a generic architecture able not only to learn via imitation but also to interact as an emerging property of the system constituted by two similar architectures with a different history. (shrink)

Christian Thomasius claims for himself the label of ‘eclectic philosopher.’ This claim first regards the emancipation of reason from any other authority, which not only allows him to claim new juridical rights but also to determine philosophy as awisdom-for-the-world. This claim is, however, narrowed by both the limits of scholastic knowledge and the undue generalizations Thomasius finds in it. The claim is intended to make room for belief, and for a faith purified of all philosophical-theological confusion, i.e., for awisdom-outside-the-world.Despite being (...) an anti-dogmatist and anti-syncretist, Thomasius’ eclectic claim never proved to be—contrary to a common statement—anti-systematic nor anti-religious. (shrink)

This article argues that Meinong’s analysis of assumption, while exploring the variety of phenomenological primitives in a more promising way than Brentano did, nevertheless fails to adequately account for the noncommittal character of assumptive attitudes and the difference between assumptive and other neighbouring attitudes. Section 1 outlines an overall framework for the philosophical analysis of assumptions and cognitive attitudes. Section 2 gives an overview of Brentano’s analysis of cognitive attitudes and some difficulties thereof. Section 3 offers a critical examination of (...) Meinong’s rival analysis. Eventually, Section 4 suggests an alternative route, according to which assumptive attitudes are best analysed in taking as a phenomenological primitive besides. (shrink)

Monotheism: the word indicates a system of thought that proceeds from a recognition of the divinity of a single god to the exclusion of all other. This exclusivity distinguishes monotheism from henotheism or monolatry and explains why monotheism is a question of belief, unlike traditional eastern religions, among them the religion of the Old Testament. The paper shows that monotheism is in fact absent from the Hebrew Bible by examining in particular the Creation stories and the vocabulary of divine oneness. (...) It is in the Roman period, particularly in Philo of Alexandria’s work, that we find more properly monotheistic writing, influenced by exegesis based on cosmogonic myths, foremost among them the biblical story known as the Creation. Imperial power would have had to assume a truly universal character for the idea of a single god assuring that power to emerge from the multitude. (shrink)

Résumé — Dans cet article, je postule qu’il y a plusieurs variétés d’antipsychologisme logique, auxquelles correspondent différents concepts de « logique pure ». Deux conceptions sont ici confrontées : la « logique de l’idéalité » de Husserl et la « logique de la validité » de Rickert. Contrairement à l’emploi équivoque des termes « validité » et « idéalité » chez Heidegger, je montre d’abord que ces deux conceptions, bien que très proches, ne sont pas parfaitement superposables, car Rickert partage (...) l’antipsychologisme de Husserl mais rejette sa théorie des significations. Il apparaît ensuite que cette divergence – particulièrement visible dans la recension inédite, par Rickert, du livre très controversé de Palágyi – touche en réalité un « point faible » des Recherches logiques de Husserl : la confusion entre les objets logiques et les idéalités mathématiques. L’alternative « axiologique » proposée par Rickert évite d’emblée cette confusion en soutenant que le sens logique des propositions, fondé sur de pures « valeurs théoriques », est irréductible à un objet idéal.— In this article, I postulate that there are several varieties of logical antipsychologism, to which correspond various concepts of “pure logic”. Two conceptions are here under discussion : Husserl’s “logic of ideality” and Rickert’s “logic of validity”. Against the equivocal use of “validity” and “ideality” by Heidegger, I first show that none of those conceptions can be exactly superimposed on the other one, because Rickert agrees with Husserl’s antipsychologism but rejects his theory of significations. It then appears that this difference – which is particularly obvious in Rickert’s unpublished review of Palágyi’s very controversial book –, reveals in fact a “weak point” in Husserl’s Logical Investigations : the confusion between logical and mathematical objects . Rickert’s “axiological” alternative avoids directly this confusion by asserting the irreducibility of the propositional sense – which is grounded on pure “theoretical values” – to an ideal object. (shrink)

Adopting a functionalist perspective, we emphasize the interest of considering imitation as a single capacity with two functions: communication and learning. These two functions both imply such capacities as detection of novelty, attraction toward moving stimuli and perception-action coupling. We propose that the main difference between the processes involved in the two functions is that, in the case of learning, the dynamics is internal to the system constituted by an individual whereas in the case of communication, the dynamics concerns the (...) system composed by the perception of one individual coupled with the action of the other. In this paper, we compare the first developmental steps of imitation in three populations: typically developing children, children with autism, and robots. We show evidence of strong correlations between imitating and being imitated in typical infants and low-functioning children with autism. Relying on this evidence, the robotic perspective is to provide a generic architecture able not only to learn via imitation but also to interact as an emerging property of the system constituted by two similar architectures with a different history. (shrink)

Clinical ethics support services are developing in Europe. They will be most useful if they are designed to match the ethical concerns of clinicians. We conducted a cross-sectional mailed survey on random samples of general physicians in Norway, Switzerland, Italy, and the UK, to assess their access to different types of ethics support services, and to describe what makes them more likely to have used available ethics support. Respondents reported access to formal ethics support services such as clinical ethics committees (...) (23%), consultation in individual cases (17.6%), and individual ethicists (8.8%), but also to other kinds of less formal ethics support (23.6%). Access to formal ethics support services was associated with work in urban hospitals. Informal ethics resources were more evenly distributed. Although most respondents (81%) reported that they would find help useful in facing ethical difficulties, they reported having used the available services infrequently (14%). Physicians with greater confidence in their knowledge of ethics (P = 0.001), or who had had ethics courses in medical school (P = 0.006), were more likely to have used available services. Access to help in facing ethical difficulties among general physicians in the surveyed countries is provided by a mix of official ethics support services and other resources. Developing ethics support services may benefit from integration of informal services. Development of ethics education in medical school curricula could lead to improved physicians sensititity to ethical difficulties and greater use of ethics support services. Such support services may also need to be more proactive in making their help available. (shrink)

Volume 20, Issue 9, September 2020, Page 76-78.

The management literature is not short of tools for helping people to make wiser decisions. This paper outlines another tool so it must be asked how can it justify itself given the substantial work that is already done. We suggest that many tools either fail to properly integrate, or simply lack an analysis of (i) showing how emotions help or hinder solving the problem, (ii) the role of creative and critical thinking and (iii), working out what values are at issue (...) in the problem. These three categories can be integrated into a decision-making procedure through an analysis of the stages of decision making. While the emphasis that is laid on these stages will differ depending upon the problem, we suggest that wise decision making requires (i) gaining an adequate understanding of the situation, (ii) working out what matters, (iii) generating options, (iv) selecting an option on the basis of what matters and (v) carrying out the option. As practical philosophers we must ask how each of these stages can be adequately carried out, and here we seek to show how philosophy, and other disciplines, can help for the three areas we identify above as lacunae. In looking at the role of emotions we base our analysis on the Aristotelian and Stoic notion that the core of emotions is that they are judgements. This analysis allows us to make sense of both the rationalist view that emotions are a hindrance, and the romantic notion that emotions are a help. Wise decision making involves unpacking emotions to see what they can reliably tell us about the situation, our values, potential options and how they can motivate us. We suggest ways this task can be achieved. Critical thinking needs to be employed throughout the decision-making procedure so that we fairly and adequately understand the situation and assess potential values and options. We outline some key skills and interventions that can be employed. Critical thinking needs material to work on so we suggest how creative thinking can be used to reframe the situation, and generate potential values and options. The driving force of making a decision is, or at least should be, the values we wish to realise with our decision; what we think matters. Some decisions are purely prudential and here we draw upon ideas of Nozick, Griffin, Aristotle and Epicurus to suggest ways the decision maker can evaluate their prudential values. For ethical decisions ideas from Mill, Kant and others can help us think through what we wish to achieve. We end with a case study to illustrate how the procedure works in practice. (shrink)

… the new figure of an event-machine would no longer be even a figure. It would not resemble, it would resemble nothing, not even what we call, in a still familiar way, a monster. But it would ther...

The foundation of Mathematics is both a logico-formal issue and an epistemological one. By the first, we mean the explicitation and analysis of formal proof principles, which, largely a posteriori, ground proof on general deduction rules and schemata. By the second, we mean the investigation of the constitutive genesis of concepts and structures, the aim of this paper. This “genealogy of concepts”, so dear to Riemann, Poincaré and Enriques among others, is necessary both in order to enrich the foundational analysis (...) with an often disregarded aspect (the cognitive and historical constitution of mathematical structures) and because of the provable incompleteness of proof principles also in the analysis of deduction. For the purposes of our investigation, we will hint here to a philosophical frame as well as to some recent experimental studies on numerical cognition that support our claim on the cognitive origin and the constitutive role of mathematical intuition. (shrink)

This paper analyses the rise of synthetic nitrogen in Great Britain and its empire, from the First World War to the aftermath of the Second World War. Rather than focus solely on technological innovations and consumption statistics, it seeks to explain how nitrogen was a central element in the expansion of a form of agricultural governance, which needed simplified, stable, and seemingly universal input/output formulae. In the first half of the twentieth century, nitrogen was thus gradually constructed as a global (...) indicator of development, as it was particularly adapted to scientific and political regimes increasingly relying upon abstraction and quantification. Yet, the history of nitrogenous fertilizers in the interwar years also shows that this cannot be reduced to a simple story of triumphant modernity, as their development and globalization was imperfect, unstable, accompanied by resistance and the resilience or emergence of other models. Rather than assuming an all-powerful “state” project, the paper thus seeks to recover the multiplicity of actors, and attempts to account for the rise of nitrogenous fertilizers; not just as the progressive application of a technological breakthrough, but as a difficult process embedded in technological, financial, and military constraints, corporate strategies, political imperatives, and the changing institutional framework of agricultural research. (shrink)

In order to promote better practices and communication around end-of-life decision-making, several Canadian hospitals in the province of Quebec have developed a tool called “Levels of Intervention”. No work to date has been published demonstrating improvement since these forms were implemented. The purpose of the present study was to obtain information about the use of LOI forms across Quebec hospitals and to identify gaps in practice as well as areas for improvement. A retrospective study was undertaken of 299 charts of (...) patients who had died in three Quebec hospitals with a LOI ordered. Results were analysed through a principlism ethical framework. High compliance with the level of intervention ordered at the time of death was recorded, as well as high involvement of patient and/or family, demonstrating the efficiency of LOI in promoting respect for autonomy. Other results show delays in end-of-life care discussions in the course of the hospitalization. Only a small proportion of patients who died had a palliative care consultation, which may reflect equity issues in access to care. This study highlights the importance of the LOI in Quebec and the role it is playing in respect for end-of-life preferences as well as in the involvement of patients and families in the decision-making process. Training specific to end-of-life decision-making conversations would help support the LOI form’s use, as would developing provincial or national guidelines on the use of LOI to standardize organizational policies and practice around end-of-life care. (shrink)

I want to concentrate on two kinds of talking about the arts. One concerns those aspects of the language of philosophical aesthetics in which generalisations about ‘art’ and ‘the arts’ are made. The other concerns the language of the critic in so far as it can be stated as having a very particular aim: ‘the stimulation’ ‘of interest and the heightening of insight and the education of his ability to make his own appreciative judgments from direct experience’.

In this article I shall employ the word “spiritual” for want of a better. It is not a particularly good word, for it is “emotive,” stirring up sentimental feelings in some people and causing the sympathies of others to shut up like clams. “Personal” is in some ways less objectionable, but a title like “The Personal Basis of Democracy” might suggest a thesis other than I have in mind. Nor is the word “moral” nearly wide enough. As to the meaning (...) of “spiritual” all I can say now is that my readers will have at least some idea of what I am referring to by the time they reach the end of the article. (shrink)

The Planteome project provides a suite of reference and species-specific ontologies for plants and annotations to genes and phenotypes. Ontologies serve as common standards for semantic integration of a large and growing corpus of plant genomics, phenomics and genetics data. The reference ontologies include the Plant Ontology, Plant Trait Ontology, and the Plant Experimental Conditions Ontology developed by the Planteome project, along with the Gene Ontology, Chemical Entities of Biological Interest, Phenotype and Attribute Ontology, and others. The project also provides (...) access to species-specific Crop Ontologies developed by various plant breeding and research communities from around the world. We provide integrated data on plant traits, phenotypes, and gene function and expression from 95 plant taxa, annotated with reference ontology terms. (shrink)

Maud Boyer Arnaud Destrebecqz Axel Cleeremans.

The interventionist account of causation offers a criterion to distinguish causes from non-causes. It also aims at defining various desirable properties of causal relationships, such as specificity, proportionality and stability. Here we apply an information-theoretic approach to these properties. We show that the interventionist criterion of causation is formally equivalent to non-zero specificity, and that there are natural, information-theoretic ways to explicate the distinction between potential and actual causal influence. We explicate the idea that the description of causes should be (...) proportional to that of their effects. Then we draw a distinction between two ideas in the existing literature, the range of invariance of a causal relationship and its stability. The range of invariance is related to specificity and range of causal values. Stability concerns the effect of additional variables on the relationship between some focal pair of cause and effect variables. We show how to distinguish and measure the direct influence of background variables on the effect variable, and their influence on the relationship between the focal cause and the effect variable. Finally, we discuss the limitations of the information-theoretic approach, and offer prospects for complementary approaches. (shrink)

In 1952, Heinrich Scholz published a question in The Journal of Symbolic Logic asking for a characterization of spectra, i.e., sets of natural numbers that are the cardinalities of finite models of first order sentences. Günter Asser in turn asked whether the complement of a spectrum is always a spectrum. These innocent questions turned out to be seminal for the development of finite model theory and descriptive complexity. In this paper we survey developments over the last 50-odd years pertaining to (...) the spectrum problem. Our presentation follows conceptual developments rather than the chronological order. Originally a number theoretic problem, it has been approached by means of recursion theory, resource bounded complexity theory, classification by complexity of the defining sentences, and finally by means of structural graph theory. Although Scholz' question was answered in various ways, Asser's question remains open. (shrink)

In this paper, we apply the perspective of intra-organismal ecology by investigating a family of ecological models suitable to describe a gene therapy to a particular metabolic disorder, the adenosine deaminase deficiency (ADA-SCID). The gene therapy is modeled as the prospective ecological invasion of an organ (here, bone marrow) by genetically modified stem cells, which then operate niche construction in the cellular environment by releasing an enzyme they synthesize. We show that depending on the chosen order (a choice that cannot (...) be made on \textit{a priori} assumptions), different kinds of dynamics are expected, possibly leading to different therapeutic strategies. This drives us to discuss several features of the extension of ecology to intra-organismal ecology. (shrink)